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Literatur und weiterführende Links (FOOD 10-13)


Literaturliste zu Vitamin A

Ahmad SM, Haskell MJ, Raqib R, Stephensen CB. Markers of innate immune function are associated with vitamin a stores in men. J Nutr. 2009;139:377-85.

Ambrosini GL, de Klerk NH, Fritschi L, Mackerras D, Musk B. Fruit, vegetable, vitamin A intakes, and prostate cancer risk. Prostate Cancer Prostatic Dis. 2008;11:61-6.

Andreozzi VL, Bailey TC, Nobre FF, et al: Random-Effects Models in Investigating the Effect of Vitamin A in Childhood Diarrhea. Ann Epidemiol, 2006;16:241-7.

Bellemère G, Stamatas GN, Bruère V, Bertin C, Issachar N, Oddos T. Antiaging action of retinol: from molecular to clinical. Skin Pharmacol Physiol. 2009;22:200-9.

Berson EL, Rosner B, Sandberg MA, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Arch Ophthalmol. 1993;111:761-772.

Berson EL, Rosner B, Sandberg MA, Weigel-DiFranco C, Brockhurst RJ, Hayes KC, Johnson EJ, Anderson EJ, Johnson CA, Gaudio AR, Willett WC, Schaefer EJ. Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch Ophthalmol. 2010;128:403-11.

Biesalski HK, Chichili GR, Frank J, von Lintig J, Nohr D. Conversion of beta-carotene to retinal pigment. Vitam Horm. 2007;75:117-30.

Biesalski HK, Nohr D. Importance of vitamin-A for lung function and development. Mol Aspects Med. 2003;24:431-40.

Biesalski HK, Tinz J. Nutritargeting. Adv Food Nutr Res. 2008;54:179-217.

Bjelakovic G, Nikolova D, Simonetti RG, et al: Antioxidant Supplements for Prevention of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. Lancet, 2004; 364:1219-28.

Bohlke K, Spiegelman D, Trichopoulou A, Katsouyanni K, Trichopoulos D. Vitamins A, C and E and the risk of breast cancer: results from a case-control study in Greece. Br J Cancer. 1999;79:23-29.

Bremner JD, McCaffery P. The neurobiology of retinoic acid in affective disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 15;32:315-31.

Butler JC, et al. Measles Severity and Serum Retinol (Vitamin A) Concentration among Children in the United States. Pediatrics. 1993;91:1176-81.

Chagan MK, Van den Broeck J, Luabeya KK, Mpontshane N, Tucker KL, Bennish ML. Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa. Eur J Clin Nutr. 2009;63:850-7.

Christian P, West KP Jr, Khatry SK, et al: Night Blindness During Pregnancy and Subsequent Mortality Among Women in Nepal: Effects of Vitamin A and Beta Carotene Supplementation. Am J Epidemiol 2000; 152:542-7.

Comstock GW, Helzlsouer KJ. Preventive nutrition and lung cancer. In: Bendich A, Decklebaum RJ, eds. Preventive Nutrition: The Comprehensive Guide for Health Professionals. 2nd ed. Totowa: Humana Press Inc; 2001:97-129.

de Botton S, Coiteux V, Chevret S, et al: Outcome of Childhood Acute Promyelocytic Leukemia With All-Trans-Retinoic Acid and Chemotherapy. J Clin Oncol 2004; 22:1404-12.

DeCicco, K.L., Zolfaghari, R., Li, N., Ross, A.C.: Retinoic acid and polyriboinosinic acid act synergistically to enhance the antibody response to tetanus toxoid during vitamin A deficiency: possible involvement of interleukin-2 receptor-beta, signal transducer and activator of transcription-1, and interferon regulatory factor-1. The Journal of Infectious Disease 2000/182 (Suppl. 1): S 29-S 36.

Duriancik DM, Lackey DE, Hoag KA. Vitamin A as a regulator of antigen presenting cells. J Nutr. 2010;140:1395-9.

Dvorak AM. Vitamin A in Crohn’s Disease. Lancet. Jun. 1980;1(8181):1303-04.

Ehrenpreis ED, Jani A, Levitsky J, et al: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy. Dis Colon Rectum 2005; 48:1-8.

Ertesvåg A, Naderi S, Blomhoff HK. Regulation of B cell proliferation and differentiation by retinoic acid. Semin Immunol. 2009;21:36-41.

Fawzi W, et al: HIV-1 Positive Mothers Taking Vitamin A Increase Risk of Transmitting HIV to Newborns. AIDS 2002; 16: 1870-5.

Fawzi WW, Msamanga G, Hunter D, et al: Randomized Trial of Vitamin Supplements in Relation to Vertical Transmission of HIV-1 in Tanzania. J Acquir Immune Defic Syndr 2000; 23:246-54.

Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54.

Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J Leukoc Biol. 2002;71:16-32.

Franceschi S. Micronutrients and breast cancer. Eur J Cancer Prev. 1997;6:535-539.

Garnock-Jones KP, Perry CM. Alitretinoin: in severe chronic hand eczema. Drugs. 2009;20:1625-34.

Hogarth CA, Griswold MD. The key role of vitamin A in spermatogenesis. J Clin Invest. 2010;1;120:956-62.

Hulten K, Van Kappel AL, Winkvist A, et al. Carotenoids, alpha-tocopherols, and retinol in plasma and breast cancer risk in northern Sweden. Cancer Causes Control. 2001;12:529-537.

Hussey GD, et al. A Randomized, Controlled Trial of Vitamin A in Children with Severe Measles. N Engl J Med 1990;323:160-64.

Johansson S, Melhus H. Vitamin A antagonizes calcium response to vitamin D in man. J Bone Miner Res. 2001;16:1899-1905.

Kafi R, Kwak HS, Schumacher WE, et al: Improvement of Naturally Aged Skin With Vitamin A (Retinol). Arch Dermatol 2007; 143:606-12.

Kokkonen J, Möttönen M, Karttunen TJ, et al: Mucosal Pathology of the Upper Gastrointestinal Tract Associated With Intensive Chemotherapy in Children: Vitamin A Supplements Do Not Prevent Lesions. Pediatr Hematol Oncol 2002; 19:181-92.

Kongnyuy EJ, Wiysonge CS, Shey MS. A systematic review of randomized controlled trials of prenatal and postnatal vitamin A supplementation of HIV-infected women. Int J Gynaecol Obstet. 2009;104:5-8.

Kuzniarz M, Mitchell P, Cumming RG, et al. Use of Vitamin Supplements and Cataract: The Blue Mountains Eye Study. Am J Ophthalmol, 2001; 132:19-26.

Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer’s disease. Expert Rev Neurother. 2009;9:1615-21.

Lin J, Song F, Yao P, Yang X, Li N, Sun S, Lei L, Liu L. Effect of vitamin A supplementation on immune function of well-nourished children suffering from vitamin A deficiency in China. Eur J Clin Nutr. 2008;62:1412-8.

Lithgow DM, et al. Vitamin A in the Treatment of Menorrhagia. S Afr Med J. 1977;51:191-93.

Long KZ, Rosado JL, Montoya Y, et al: Effect of Vitamin A and Zinc Supplementation on Gastrointestinal Parasitic Infections Among Mexican Children. Pediatrics, 2007; 120:846-55.

Longnecker MP, Newcomb PA, Mittendorf R, Greenberg ER, Willett WC. Intake of carrots, spinach, and supplements containing vitamin A in relation to risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 1997;6:887-892.

Luo M, Estívariz CF, Schleicher RL, Bazargan N, Leader LM, Galloway JR, Ziegler TR. Prospective analysis of serum carotenoids, vitamin A, and tocopherols in adults with short bowel syndrome undergoing intestinal rehabilitation. Nutrition. 2009;25:400-7.

Maden M. Retinoic acid in the development, regeneration and maintenance of the nervous system. Nat Rev Neurosci. 2007;8:755-65.

Manicassamy S, Pulendran B. Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages. Semin Immunol. 2009;21:22-7.

McGrane MM. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. J Nutr Biochem. 2007;18:497-508.

Mehta S, Fawzi W. Effects of vitamins, including vitamin A, on HIV/AIDS patients. Vitam Horm. 2007;75:355-83.

Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med. 2003;348:287-294.

Michels KB, Holmberg L, Bergkvist L, Ljung H, Bruce A, Wolk A. Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women. Int J Cancer. 2001;91:563-567.

Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol. 2008;8:685-98.

Mucida D, Park Y, Cheroutre H. From the diet to the nucleus: vitamin A and TGF-beta join efforts at the mucosal interface of the intestine. Semin Immunol. 2009;21:14-21.

Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334:1150-1155.

Pan J, Baker KM. Retinoic acid and the heart. Vitam Horm. 2007;75:257-83.

Penniston KL, Tanumihardjo SA. The acute and chronic toxic effects of vitamin A. Am J Clin Nutr 2006;83:191-201.

Petrie K, Zelent A, Waxman S. Differentiation therapy of acute myeloid leukemia: past, present and future. Curr Opin Hematol. 2009;16:84-91.

Poulain S, Evenou F, Carré MC, Corbel S, Vignaud JM, Martinet N. Vitamin A/retinoids signalling in the human lung. Lung Cancer. 2009;66:1-7.

Prakash P, Krinsky NI, Russell RM. Retinoids, carotenoids, and human breast cancer cell cultures: a review of differential effects. Nutr Rev. 2000;58:170-176.

Reifen R. Vitamin A as an anti-inflammatory agent. Proc Nutr Soc. 2002 Aug;61:397-400.

Rejnmark L, Vestergaard P, Charles P, et al. No effect of vitamin A intake on bone mineral density and fracture risk in perimenopausal women. Osteoporos Int. 2004;15:872-880.

Ribaya-Mercado JD, Blumberg JB. Vitamin A: is it a risk factor for osteoporosis and bone fracture? Nutr Rev. 2007;65:425-38.

Ross AC. Vitamin A and retinoids. In: Shils M, ed. Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:305-327.

Ross AC. Vitamin A supplementation and retinoic acid treatment in the regulation of antibody responses in vivo. Vitam Horm. 2007;75:197-222.

Rotondi MA, Khobzi N. Vitamin A supplementation and neonatal mortality in the developing world: a meta-regression of cluster-randomized trials. Bull World Health Organ. 2010;88:697-702.

Semba RD, et al. Increased Mortality Associated with Vitamin A Deficiency during Human Immunodeficiency Virus Type 1 Infection. Arch Intern Med 1993;153:2149-54.

Steck-Scott S, Forman MR, Sowell A, et al: Carotenoids, Vitamin A and Risk of Adenomatous Polyp Recurrence in the Polyp Prevention Trial. Int J Cancer, 2004; 112:295-305.

Suharno D, West CE, Muhilal, Karyadi D, Hautvast JG. Supplementation with vitamin A and iron for nutritional anaemia in pregnant women in West Java, Indonesia. Lancet 1993;342:1325-1328.

Swami HM, Thakur JS, and Bhatia SP: Impact of Mass Supplementation of Vitamin A. Indian J Pediatr, 2007; 74:443-7.

Tafti M, Ghyselinck NB. Functional implication of the vitamin A signaling pathway in the brain. Arch Neurol. 2007;64:1706-11.

Tallman MS, Andersen JW, Schiffer CA, et al: All-Trans Retinoic Acid in Acute Promyelocytic Leukemia: Long-Term Outcome and Prognostic Factor Analysis From the North American Intergroup Protocol. Blood 2002; 100:4298-302.

Tom WL, Peng DH, Allaei A, et al: The Effect of Short-Contact Topical Tretinoin Therapy for Foot Ulcers in Patients With Diabetes. Arch Dermatol, 2005; 141:1373-7.

Varandas L, Julien M, Gomes A, et al: A Randomised, Double-Blind, Placebo-Controlled Clinical Trial of Vitamin A in Severe Malaria in Hospitalised Mozambican Children. Ann Trop Paediatr 2001; 21:211-22.

Vetrugno M, Maino A, Cardia G, et al: A Randomised, Double Masked, Clinical Trial of High Dose Vitamin A and Vitamin E Supplementation After Photorefractive Keratectomy. Br J Ophthalmol 2001; 85:537-9.

Vitoux D, Nasr R, de The H. Acute promyelocytic leukemia: new issues on pathogenesis and treatment response. Int J Biochem Cell Biol. 2007;39:1063-70.

Wang WP: Effects of Vitamin A Nutritional Status on the Immune Functions in Young Infants – Reflection of Relationship Between Nutrition and Immunity in Childhood. Zhonghua Er Ke Za Zhi 2006; 44:3-6.

Weinstock MA, Bingham SF, Lew RA, Hall R, Eilers D, Kirsner R, Naylor M, Kalivas J, Cole G, Marcolivio K, Collins J, Digiovanna JJ, Vertrees JE; Veterans Affairs Topical Tretinoin Chemoprevention (VATTC) Trial Group. Topical tretinoin therapy and all-cause mortality. Arch Dermatol. 2009;145:18-24.

Wylie-Rosett JA, et al. Influence of Vitamin A on Cervical Dysplasia and Carcinoma in Situ. Nutr Cancer. 1984;6:49-57.

Zhang S, Hunter DJ, Forman MR, et al. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999;91:547-556.

Zhou GB, Li G, Chen SJ, Chen Z. From dissection of disease pathogenesis to elucidation of mechanisms of targeted therapies: leukemia research in the genomic era. Acta Pharmacol Sin. 2007;28:1434-49.

Zimmermann MB, Jooste PL, Mabapa NS, et al: Vitamin A Supplementation in Iodine-Deficient African Children Decreases Thyrotropin Stimulation of the Thyroid and Reduces the Goiter Rate. Am J Clin Nutr 2007, 86:1040-4.


Literaturliste zu Vitamin E

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol. 2001;119:1439-1452.

Ahuja JK, Goldman JD, Moshfegh AJ. Current status of vitamin E nutriture. Ann N Y Acad Sci. 2004;1031:387-390.

Alkhenizan A, Hafez K. The role of vitamin E in the prevention of cancer: a meta-analysis of randomized controlled trials. Ann Saudi Med. 2007;27:409-414.

Argyriou AA, Chroni E, Koutras A, et al: A Randomized Controlled Trial Evaluating the Efficacy and Safety of Vitamin E Supplementation for Protection Against Cisplatin-Induced Peripheral Neuropathy: Final Results. Support Care Cancer 2006; 14:1134-40.

Azen SP, Qian D, Mack WJ, et al. Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering. Circulation. 1996;94:2369-2372.

Barton DL, Loprinzi CL, Quella SK, Sloan JA, Veeder MH, Egner JR, Fidler P, Stella PJ, Swan DK, Vaught NL, Novotny P. Prospective evaluation of vitamin E for hot flashes in breast cancer survivors. J Clin Oncol. 1998;16:495-500.

Beharka A, Redican S, Leka L, Meydani SN. Vitamin E status and immune function. Methods Enzymol. 1997;282:247-63.

Berson EL, Rosner B, Sandberg MA, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Arch Ophthalmol. 1993;111:761-772.

Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 2007;297:842-857.

Brigelius-Flohe R, Kelly FJ, Salonen JT, Neuzil J, Zingg J, Azzi A: The European perspective on vitamin E: current knowledge and future research. Am J Clin 2002; Nutr 76, 703-716.

Brown BG, Zhao XQ, Chait A, et al: Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease. N Engl J Med, 2001; 345:1583-92.

Cherubini A, Zuliani G, Costantini F, et al. High vitamin E plasma levels and low low-density lipoprotein oxidation are associated with the absence of atherosclerosis in octogenarians. J Am Geriatr Soc. 2001;49(5):651-654.

Dusinska M, Kazimirova A, Barancokova M, et al: Nutritional Supplementation With Antioxidants Decreases Chromosomal Damage in Humans. Mutagenesis 2003; 18:371-6.

Edmonds SE, et al. Putative Analgesic Activity of Repeated Oral Doses of Vitamin E in the Treatment of Rheumatoid Arthritis. Results of a Prospective Placebo Controlled Double-blind Trial. Ann Rheum Dis. 1997;56:649-55.

Eidelman RS, Hollar D, Hebert PR, Lamas GA, Hennekens CH. Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease. Arch Intern Med. 2004;164:1552-1556.

El-Housseiny AA, Saleh SM, El-Masry AA, et al: The Effectiveness of Vitamin ‘E’ in the Treatment of Oral Mucositis in Children Receiving Chemotherapy. J Clin Pediatr Dent, 2007; 31:167-70.

Gale CR, Ashurst HE, Powers HJ, Martyn CN. Antioxidant vitamin status and carotid atherosclerosis in the elderly. Am J Clin Nutr. 2001;74:402-408.

Gibbons RJ, Abrams J, Chatterjeek K, et al: ACC/AHA 2002 Guideline Update For the Management of Patients With Chronic Stable Angina – Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). J Am Coll Cardiol 2003; 41:159-68.

Glynn RJ, Ridker PM, Goldhaber SZ, et al: Effects of Random Allocation to Vitamin E Supplementation on the Occurrence of Venous Thromboembolism: Report From the Women’s Health Study. Circulation, 2007; 116:1497-503.

Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women’s Health Study. Circulation. 2007;116:1497-1503.

Graat JM, Schouten EG, and Kok FJ: Effect of Daily Vitamin E and Multivitamin-Mineral Supplementation on Acute Respiratory Tract Infections in Elderly Persons: A Randomized Controlled Trial. JAMA 2002; 288:715-21.

Gritz DC, Srinivasan M, Smith SD, et al. The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol. 2006;90:847-851.

Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto miocardico. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto miocardico. Lancet. 1999;354(9177):447-455.

Han SN, Meydani SN. Vitamin E and infectious diseases in the aged. Proc Nutr Soc. 1999;58:697-705.

Helzlsouer KJ, Huang HY, Alberg AJ, et al. Association between alpha-tocopherol, gamma-tocopherol, selenium, and subsequent prostate cancer. J Natl Cancer Inst. 2000;92:2018-2023.

Hernandez LM, Wu X, Lin J, et al: Intake of Vitamin E (2-R Isomers of Alpha-Tocopherl) and Gamma-Tocopherol in a Case-Control Study and Bladder Cancer Risk. Proceedings of the AACR, Abstract 3921, Volume 45, March 2004.

Hodis HN, Mack WJ, LaBree L, et al: Alpha-Tocopherol Supplementation in Healthy Individuals Reduces Low-Density Lipoprotein Oxidation But Not Atherosclerosis: The Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation 2002; 106:1453-9.

Jiang Q, Christen S, Shigenaga MK, Ames BN. gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr. 2001;74:714-722.

Ju J, Picinich SC, Yang Z, Zhao Y, Suh N, Kong AN, Yang CS. Cancer-preventive activities of tocopherols and tocotrienols. Carcinogenesis. 2010 ;31:533-42.

Karlson EW, Shadick NA, Cook NR, Buring JE, Lee IM. Vitamin E in the primary prevention of rheumatoid arthritis: the Women’s Health Study. Arthritis Rheum.2008; 15;59:1589-95.

Keith ME, Jeejeebhoy KN, Langer A, et al: A Controlled Clinical Trial of Vitamin E Supplementation in Patients With Congestive Heart Failure. Am J Clin Nutr, 2001; 73:219-24.

Kleijnen J and Mackerras D: Vitamin E for Intermittent Claudication. Cochrane Database Syst Rev, 2000, (2):CD000987.

Klein EA, Thompson IM, Lippman SM, et al. SELECT: the next prostate cancer prevention trial. Selenum and Vitamin E Cancer Prevention Trial. J Urol. 2001;166:1311-1315.

Kölsch H, Ludwig M, Lütjohann D, Rao ML. Neurotoxicity of24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17 beta. J Neural Transm. 2001;108:475-88.

Kontush K, Schekatolina S. Vitamin E in neurodegenerative disorders: Alzheimer’s disease. Ann N Y Acad Sci. 2004;1031:249-262.

Kushi LH, Folsom AR, Prineas RJ, Mink PJ, Wu Y, Bostick RM. Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. N Engl J Med. 1996;334:1156-1162.

Lee IM, Cook NR, Gaziano JM, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women’s Health Study: a randomized controlled trial. JAMA. 2005;294:56-65.

Li GX, Lee MJ, Liu AB, Yang Z, Lin Y, Shih WJ, Yang CS. δ-tocopherol is more active than α – or γ -tocopherol in inhibiting lung tumorigenesis in vivo. Cancer Prev Res (Phila). 2011;4:404-13.

Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009;301:39-51.

London RS, et al. Efficacy of Alpha-tocopherol in the Treatment of the Premenstrual Syndrome. J Reprod Med. 1987;32:400-04.

Lonn E, Bosch J, Yusuf S, et al. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA. 2005;293:1338-1347.

Malafa MP, Neitzel LT. Vitamin E succinate promotes breast cancer tumor dormancy. J Surg Res. 2000;93:163-170.

Manzella D, Barbieri M, Ragno E, et al: Chronic Administration of Pharmacologic Doses of Vitamin E Improves the Cardiac Autonomic Nervous System in Patients With Type 2 Diabetes. Am J Clin Nutr, 2001, 73:1052-7.

Mark SD, Qiao YL, Dawsey SM, et al: Prospective Study of Serum Selenium Levels and Incident Esophageal and Gastric Cancers. J Natl Cancer Inst, 2000, 92(21):1753-63.

Masaki KH, Losonczy KG, Izmirlian G, et al. Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Neurology. 2000;54:1265-1272.

McNeil JJ, Robman L, Tikellis G, Sinclair MI, McCarty CA, Taylor HR. Vitamin E supplementation and cataract: randomized controlled trial. Ophthalmology. 2004;111:75-84.

McQuillan BM, Hung J, Beilby JP, Nidorf M, Thompson PL. Antioxidant vitamins and the risk of carotid atherosclerosis. The Perth Carotid Ultrasound Disease Assessment study (CUDAS). J Am Coll Cardiol. 2001;38:1788-1794.

Meydani M. Antioxidants and cognitive function. Nutr Rev. 2001;59(8 Pt 2):S75-80

Meydani SN, Leka LS, Fine BC, et al. Vitamin E and Respiratory Tract Infections in Elderly Nursing Home Residents. JAMA 2004;292:828-836.

Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142:37-46.

Miwa K, Igawa A, Nakagawa K, Hirai T, Inoue H. Consumption of vitamin E incoronary circulation in patients with variant angina. Cardiovasc Res. 1999Jan;41(1):291-8.

Montaño Velázquez BB, Jáuregui-Renaud K, Bañuelos Arias Adel C, et al: Vitamin E Effects on Nasal Symptoms and Serum Specific IgE Levels in Patients With Perennial Allergic Rhinitis. Ann Allergy Asthma Immunol, 2006, 96:45-50.

Montonen J, Knekt P, Jarvinen R, et al: Dietary Antioxidant Intake and Risk of Type 2 Diabetes. Diabetes Care 2004, 27:362-6.

Morris CD and Carson S: Routine Vitamin Supplementation to Prevent Cardiovascular Disease: A Summary of the Evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2003, 139:56-70.

Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA.Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 ;81:508-14.

Neuzil J, Weber T, Schroder A, et al. Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements. FASEB J. 2001;15:403-415.

Packer L, Weber Su, Rimbach G: Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J Nutr 2001; 131, 369S-373S.

Packer L. Vitamin E: Biological activity and health benefits: Overview. In: Packer L and Fuchs J (Eds.) Vitamin E in health and disease. Marcel Dekker Inc.1993, New York.

Palan PR, et al. Plasma Levels of Antioxidant Beta-carotene and Alpha-tocopherol in Uterine Cervix Dysplasias and Cancer. Nutr Cancer. 1991;15:13-20.

Pathak A, Roth P, Piscitelli J, et al: Effects of Vitamin E Supplementation During Erythropoietin Treatment of the Anaemia of Prematurity. Arch Dis Child Fetal Neonatal Ed, 2003, 88:F324-8.

Petersen RC, Thomas RG, Grundman M, et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352(23):2379-2388.

Pham DQ, Plakogiannis R. Vitamin E supplementation in Alzheimer’s disease, Parkinson’s disease, tardive dyskinesia, and cataract: Part 2. Ann Pharmacother. 2005 Dec;39:2065-72.

Quin J, Engle D, Litwiller A, et al. Vitamin E succinate decreases lung cancer tumor growth in mice. J Surg Res. 2005;127:139-143.

Rapola JM, Virtamo J, Ripatti S, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet. 1997;349(9067):1715-1720.

Schuelke M: Ataxia With Vitamin E Deficiency. GeneReviews [Internet], Pagon RA, Bird TC, Dolan CR, et al, eds, Seattle, WA: University of Washington, Seattle, 1993-2005.

Shekelle PG, Morton SC, Jungvig LK, et al: Effect of Supplemental Vitamin E for the Prevention and Treatment of Cardiovascular Disease. J Gen Intern Med, 2004; 19:380-9.

Simon E, Gariepy J, Cogny A, Moatti N, Simon A, Paul JL. Erythrocyte, but not plasma, vitamin E concentration is associated with carotid intima-media thickening in asymptomatic men at risk for cardiovascular disease. Atherosclerosis. 2001;159:193-200.

Slatore CG, Littman AJ, Au DH, Satia JA, White E. Long-term use of supplemental multivitamins, vitamin C, vitamin E, and folate does not reduce the risk of lung cancer. Am J Respir Crit Care Med. 2008;177:524-530.

Soares-Weiser K, Maayan N, McGrath J. Vitamin E for neuroleptic-inducedtardive dyskinesia. Cochrane Database Syst Rev. 2011 Feb 16;(2):CD000209.

Traber MG, Frei B, Beckman JS. Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol. 2008;19:30-38.

U.S. Preventive Services Talk Force: Routine Vitamin Supplementation to Prevent Cancer and Cardiovascular Disease. Recommendations and Rationale. Ann Int Med, 2003; 139:51-5.

Venkateswaran V, Fleshner NE, and Klotz LH: Synergistic Effect of Vitamin E and Selenium in Human Prostate Cancer Cell Lines. Prostate Cancer Prostatic Dis, 2004; 7:54-6.

Vetrugno M, Maino A, Cardia G, et al: A Randomised, Double Masked, Clinical Trial of High Dose Vitamin A and Vitamin E Supplementation After Photorefractive Keratectomy. Br J Ophthalmol, 2001, 85:537-9.

Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet. 2003;361(9374):2017-2023.

Walker M, Samii A. Delayed onset of ataxia in a patient with short bowelsyndrome: a case of vitamin E deficiency. Nutr Neurosci. 2004;7:191-3.

West AL, Oren GA, Moroi SE. Evidence for the use of nutritional supplements and herbal medicines in common eye diseases. Am J Ophthalmol. 2006;141:157-166.

Yang CS, Lu G, Ju J, Li GX. Inhibition of inflammation and carcinogenesis in the lung and colon by tocopherols. Ann N Y Acad Sci. 2010 ;1203:29-34.

You H, Yu W, Munoz-Medellin D, Brown PH, Sanders BG, Kline K. Role of extracellular signal-regulated kinase pathway in RRR-alpha-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells. Mol Carcinog. 2002;33:228-236.

Yu W, Sanders BG, Kline K. RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria. Cancer Res. 2003;63:2483-2491.

Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):154-160.

Ziaei S, Faghihzadeh S, Sohrabvand F, et al: A Randomised Placebo-Controlled Trial to Determine the Effect of Vitamin E in Treatment of Primary Dysmenorrhoea. BJOG 2001 108(11):1181-3.


Literaturliste zu Vitamin D

Ahn J, Peters U, Albanes D, Purdue MP, Abnet CC, Chatterjee N, et al: Serum vitamin D concentration and prostate cancer risk: a nested case-control study. Journal of the National Cancer Institute 2008; 100 : 796–804.

Andreassen H, et al: Regulators of Calcium Homeostasis and Bone Mineral Density in Patients with Crohn’s Disease. Scand J Gastroenterol 1998;33:1087-1093.

Basile LA, Taylor SN, Wagner CL, et al: The Effect of High-Dose Vitamin D Supplementation on Serum Vitamin D Levels and Milk Calcium Concentration in Lactating Women and Their Infants. Breastfeed Med 2006; 1:27-35.

Bertone-Johnson E, Chen WY, Holick MF, Hollis BW, Colditz G, Willett WC, et al: Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer. Cancer Epidemiology, Biomarkers and Prevention 2005; 14 : 1991–1997.

Bertone-Johnson ER, Hankinson SE, Bendich A, et al: Calcium and Vitamin D Intake and Risk of Incident Premenstrual Syndrome. Arch Intern Med 2005; 165:1246-1252.

Bischoff HA, Stahelin HB, Dick W, et al: Effects of Vitamin D and Calcium Supplementation on Falls: A Randomized Controlled Trial. J Bone Miner Res 2003; 18:343-351.

Bischoff-Ferrari HA, Borchers M, Gudat F, Durmuller U, Stahelin HB, Dick W: Vitamin D receptor expression in human muscle tissue decreases with age. J Bone Miner Res 2004; 19: 265—269.

Bischoff-Ferrari HA, Can U, Staehelin HB, et al: Severe vitamin D deficiency in Swiss hip fracture patients. Bone 2008; 42: 597—602.

Bischoff-Ferrari HA, Dawson-Hughes B, Platz A, et al: Effect of high-dosage cholecalciferol and extended physiotherapy on complications after hip fracture: a randomized controlled trial. Arch Intern Med 2010;170: 813–820.

Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, et al: Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomized controlled trials. BMJ 2009; 339: b3692.

Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B: Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 2006;84:18-28.

Bischoff-Ferrari HA, Shao A, Dawson-Hughes B, Hathcock J, Giovannucci E, Willett WC: Benefit-risk assessment of vitamin D supplementation. Osteoporosis Int 2009; 3: 3

Borissova AM, Tankova T, Kirilov G, Dakovska L, Kovacheva R: The effect of vitamin D3 on insulin secretion and peripheral insulin sensitivity in type 2 diabetic patients. Int J Clin Pract 2003;57:258-261.

Bouillon R, Bischoff-Ferrari H, Willett W: Vitamin D and health: perspectives from mice and man. J Bone Miner Res 2008; 23: 974—979.

Broe KE, Chen TC, Weinberg J, Bischoff-Ferrari HA, Holick MF, Kiel DP: A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study. J Am Geriatr Soc 2007;55:234-239.

Caan B, Neuhouser M, Aragaki A, et al: Calcium Plus Vitamin D Supplementation and the Risk of Postmenopausal Weight Gain. Arch Intern Med 2007; 167:893-902.

Cannell JJ, Vieth R, Umhau JC, et al. Epidemic influenza and vitamin D. Epidemiol Infect. 2006;134:1129–1140.

Chel V, Wijnhoven HA, Smit JH, Ooms M, Lips P: Efficacy of different doses and time intervals of oral vitamin D supplementation with or without calcium in elderly nursing home residents. Osteoporos Int 2008; 19: 663—671.

DeLuca HF : Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 2004;80:1689-1696.

Deluca HF, Cantorna MT: Vitamin D: its role and uses in immunology. FASEB J 2001;15:2579-2585.

Deroisy R, Collette J, Albert A, et al: Administration of a Supplement Containing Both Calcium and Vitamin D Is More Effective Than Calcium Alone to Reduce Secondary Hyperparathyroidism in Postmenopausal Women With Low 25(OH)Vitamin D Circulating Levels. Aging Clin Exp Res 2002; 14:13-17.

Ding EL, Mehta S, Fawzi WW, Giovannucci EL: Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: Reanalysis of Women’s Health Initiative randomized trial. International Journal of Cancer 2008; 122 : 1690–1694.

Dubnig H, Pilz S, Scharnagl H, et al: Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause and Cardiovascular Mortality. Arch Intern Med 2008; 168:1340-1349.

Dukas L, Bischoff HA, Lindpaintner LS, et al: Alfacalcidol Reduces the Number of Fallers in a Community-Dwelling Elderly Population With a Minimum Calcium Intake of More Than 500 mg Daily. J Am Geriatr Soc 2004; 52:230-236.

Feskanich D, Ma J, Fuchs CS, et al: Plasma vitamin D metabolites and risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev 2004;13:1502-1508.

Forman JP, Giovannucci E, Holmes MD, et al: Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension. Hypertension 2007; 19: 19.

Freedman DM, Dosemeci M, McGlynn K: Sunlight and mortality from breast, ovarian, colon, prostate, and non-melanoma skin cancer: a composite death certificate based case-control study. Occupational and Environmental Medicine 2002; 59: 257–262.

Freedman DM, Looker AC, Chang SC, Graubard BI: Prospective study of serum vitamin D and cancer mortality in the United States. Journal of the National Cancer Institute 2007; 99 : 1594–1602.

Gallagher JC: The Effects of Calcitriol on Falls and Fractures and Physical Performance Tests. J Steroid Biochem Mol Biol 2004; 89-90:497-501.

Garland CF, Gorham ED, Mohr SB, et al: Vitamin D and prevention of breast cancer: pooled analysis. J Steroid Biochem Mol Biol 2007;103:708-711.

Ginde AA, Mansbach JM, Camargo CA, Jr : Association between serum 25 hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 2009; 169: 384—390.

Giovannucci E, Liu Y, Hollis BW, Rimm EB: 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 2008; 168: 1174—1180.

Giovannucci E, Liu Y, Rimm EB, et al: Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst 2006; 98: 451—459.

Glerup H, Mikkelsen K, Poulsen L, et al: Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement. Calcif Tissue Int 2000; 66: 419–424.

Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, et al: Optimal vitamin D status for colorectal cancer prevention. A quantitative meta-analysis. American Journal of Preventive Medicine 2007; 32 : 210–216.

Grant WB: An Estimate of Premature Cancer Mortality in the U.S. Due to Inadequate Doses of Solar Ultraviolet-B Radiation. Cancer, 2002 94:1867-75.

Grau MV, Baron JA, Sandler RS, Haile RW, Beach ML, Church TR, et al: Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trail. Journal of the National Cancer Institute 2003; 95: 1765–1771.

Holick MF: Vitamin D: Importance in the Prevention of Cancers, Type 1 Diabetes, Heart Disease, and Osteoporosis. Am J Clin Nutr 2004, 79:362-71.

Houghton LA, Vieth R: The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr 2006;84:694-697.

Hsia J, Heiss G, Ren H, et al: Calcium/Vitamin D Supplementation and Cardiovascular Events. Circulation 2007; 115:846-854.

Hypponen E, Laara E, Reunanen A, et al: Intake of Vitamin D and Risk of Type 1 Diabetes: A Birth-Cohort Study. Lancet 2001; 358:1500-1503.

Lappe JM, Travers-Gustafson D, Davies KM, et al: Vitamin D and Calcium Supplementation Reduces Cancer Risk: Results of a Randomized Trial. Am J Clin Nutr 2007, 85:1586-91.

Lee P, Greenfield JR, and Campbell LV: Vitamin D Insufficiency − A Novel Mechanism of Statin-Induced Myalgia?. Clin Endocrinol (Oxf) 2009; 71:154-155.

Liu PT, Stenger S, Li H, et al: Toll-Like Receptor Triggering of a Vitamin D Mediated Human Antimicrobial Response. Science 2006; 23: 23.

Lyons RA, Johansen A, Brophy S, et al: Preventing Fractures Among Older People Living in Institutional Care: A Pragmatic Randomised Double Blind Placebo Controlled Trial of Vitamin D Supplementation. Osteoporos Int 2007; 18:811-818.

Malluche HH, Monier-Faugere MC, and Koszewski NJ: Use and Indication of Vitamin D and Vitamin D Analogues in Patients With Renal Bone Disease. Nephrol Dial Transplant 2002; 17:6-9.

Martineau AR, Wilkinson RJ, Wilkinson KA, et al: A Single Dose of Vitamin D Enhances Immunity to Mycobacteria. Am J Respir Crit Care Med 2007; 176:208-213.

Martinez ME, Giovannucci EL, Colditz GA, et al: Calcium, vitamin D, and the occurrence of colorectal cancer among women. J Natl Cancer Inst 1996; 88:1375-1382.

Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell LA, Saag KG: Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women’s Health Study. Arthritis Rheum 2004;50 : 72-77.

Mikati MA, Dib L, Yamout B, et al: Two Randomized Vitamin D Trials in Ambulatory Patients on Anticonvulsants: Impact on Bone. Neurology 2006; 67:2005-2014.

Munger KL, Zhang SM, O’Reilly E, et al: Vitamin D Intake and Incidence of Multiple Sclerosis. Neurology 2004; 62:60-65.

Newton S, Owusu-Agyei S, Ampofo W, et al: Vitamin A Supplementation Enhances Infants’ Immune Responses to Hepatitis B Vaccine But Does Not Affect Responses to Haemophilus influenzae Type B Vaccine. J Nutr 2007; 137:1272-1277.

Ng K, Meyerhardt JA, Wu K, Feskanich D, Hollis BW, Giovannucci EL, et al: Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer. Journal of Clinical Oncology 2008; 26: 2984–1991.

Park SY, Murphy SP, Wilkens LR, Stram DO, Henderson BE, Kolonel LN: Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study. American Journal of Epidemiology 2007; 166 : 1259–1269.

Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C: Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab 2001;86:1633-1637.

Pfeifer M, Begerow B, Minne HW, Suppan K, Fahrleitner-Pammer A, Dobnig H: Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community- dwelling older individuals. Osteoporos Int 2009; 20: 315—322.

Pilz S, Dobnig H, Nijpels G, et al: Vitamin D and mortality in older men and women. Clin Endocrinol (Oxf) 2009; 18: 18.

Prabhala A, Garg R, and Dandona P: Severe Myopathy Associated With Vitamin D Deficiency in Western New York. Arch Intern Med 2000; 160:1199-1203.

Rukin N, Blagojevic M, Luscombe CJ, Liu S, Saxby MF, Ramachandran S, et al: Associations between timing of exposure to ultraviolet radiation, T-stage and survival in prostate cancer. Cancer Detection and Prevention 2007; 31: 443–449.

Schleithoff SS, Zittermann A, Tenderich G, et al: Vitamin D Supplementation Improves Cytokine Profiles in Patients With Congestive Heart Failure: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Clin Nutr 2006; 83:754-759.

Schumann SA and Ewigman B: Double-Dose Vitamin D Lowers Cancer Risk in Women Over 55. J Fam Pract 2007; 56:907-910.

Wactawski-Wende J, Kotchen JM, Anderson GL, et al: Calcium Plus Vitamin D Supplementation and the Risk of Colorectal Cancer. N Engl J Med 2006; 354:684-96.

Wang TJ, Pencina MJ, Booth SL, et al: Vitamin D Deficiency and Risk of Cardiovascular Disease. Circulation 2008; 117:503-511.

White JH: Vitamin D signaling, infectious diseases, and regulation of innate immunity. Infect Immun 2008; 76: 3837—3843.

Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL: A nested case-control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer. Journal of the National Cancer Institute 2007; 99 : 1120–1129.


Literaturliste zu Vitamin K

Binkley N, Harke J, Krueger D, Engelke J, Vallarta-Ast N, Gemar D, Checovich M, Chappell R, Suttie J. Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North American women. J Bone Miner Res 2009 ;24:983-91.

Bolton-Smith C, McMurdo ME, Paterson CR, et al. Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women. J Bone Miner Res 2007;22:509-519.

Bonjour JP, Guéguen L, Palacios C, Shearer MJ, Weaver CM. Minerals and vitamins in bone health: the potential value of dietary enhancement. Br J Nutr. 2009 Jun;101(11):1581-96. Kim M, Kim H, Sohn C. Relationship between vitamin K status, bone mineral density, and hs-CRP in young Korean women. Nutr Res Pract 2010 ;4:507-14.

Booth SL, Dallal G, Shea MK, Gundberg C, Peterson JW, Dawson-Hughes B. Effect of vitamin K supplementation on bone loss in elderly men and women. J Clin Endocrinol Metab 2008;93:1217-23.

Booth SL, Mayer J. Warfarin use and fracture risk. Nutr Rev 2000;58:20-22.

Braam LA, Knapen MH, Geusens P, et al. Vitamin K1 supplementation retards bone loss in postmenopausal women between 50 and 60 years of age. Calcif Tissue Int 2003;73:21-26.

Caraballo PJ, Heit JA, Atkinson EJ, et al. Long-term use of oral anticoagulants and the risk of fracture. Arch Intern Med. 1999;159:1750-1756.

Cashman KD, Seamans K. Bone health, genetics, and personalised nutrition. Genes Nutr. 2007;2:47-51.

Cheung AM, Tile L, Lee Y, Tomlinson G, Hawker G, Scher J, Hu H, Vieth R, Thompson L, Jamal S, Josse R. Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial. PLoS Med 2008;14;5:e196.

Cockayne S, Adamson J, Lanham-New S, Shearer MJ, Gilbody S, Torgerson DJ. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med 2006;166:1256-1261.

Costakos DT, Greer FR, Love LA, Dahlen LR, Suttie JW. Vitamin K prophylaxis for premature infants: 1 mg versus 0.5 mg. Am J Perinatol. 2003;20:485-490.

Cranenburg EC, Koos R, Schurgers LJ, Magdeleyns EJ, Schoonbrood TH, Landewé RB, Brandenburg VM, Bekers O, Vermeer C. Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species. Thromb Haemost 2010;104:811-22.

Cranenburg EC, Vermeer C, Koos R, Boumans ML, Hackeng TM, Bouwman FG, Kwaijtaal M, Brandenburg VM, Ketteler M, Schurgers LJ. The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. J Vasc Res 2008;45:427-36.

Feskanich D, Weber P, Willett WC, Rockett H, Booth SL, Colditz GA. Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr. 1999;69:74-79.

Fisher L, Byrnes E, Fisher AA. Prevalence of vitamin K and vitamin D deficiency in patients with hepatobiliary and pancreatic disorders. Nutr Res. 2009;29:676-83.

Furie B, Bouchard BA, Furie BC. Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid. Blood. 1999;93:1798-1808.

Fusaro M, Crepaldi G, Maggi S, Galli F, D’Angelo A, Calò L, Giannini S, Miozzo D, Gallieni M. Vitamin K, bone fractures, and vascular calcifications in chronic kidney disease: An important but poorly studied relationship. J Endocrinol Invest. 2011;34:317-23.

Gage BF, Birman-Deych E, Radford MJ, Nilasena DS, Binder EF. Risk of osteoporotic fracture in elderly patients taking warfarin: results from the National Registry of Atrial Fibrillation 2. Arch Intern Med. 2006;166:241-246.

Iwamoto J, Sato Y, Takeda T, Matsumoto H. Bone quality and vitamin K2 in type 2 diabetes: review of preclinical and clinical studies. Nutr Rev. 2011;69:162-7.

Iwamoto J, Sato Y, Takeda T, Matsumoto H. High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature. Nutr Res. 2009;29:221-8.

Jagannath VA, Fedorowicz Z, Thaker V, Chang AB. Vitamin K supplementation for cystic fibrosis. Cochrane Database Syst Rev 2011 19;(1):CD008482.

Jie KS, Bots ML, Vermeer C, Witteman JC, Grobbee DE. Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: a population-based study. Atherosclerosis 1995;116:117-123.

Jones KS, Bluck LJ, Wang LY, Stephen AM, Prynne CJ, Coward WA. The effect of different meals on the absorption of stable isotope-labelled phylloquinone. Br J Nutr 2009;102:1195-202.

Kasatkar P, Shetty S, Ghosh K. Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century! Blood Coagul Fibrinolysis. 2010;21:608-10.

Kidd PM. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Altern Med Rev 2010;15:199-222.

Klebanoff MA, Read JS, Mills JL, Shiono PH. The risk of childhood cancer after neonatal exposure to vitamin K. N Engl J Med 1993;329: 905-908.

Krueger T, Westenfeld R, Schurgers L, Brandenburg V. Coagulation meets calcification: the vitamin K system. Int J Artif Organs. 2009;32:67-74.

Kumar D, Greer FR, Super DM, Suttie JW, Moore JJ. Vitamin K status of premature infants: implications for current recommendations. Pediatrics 2001;108:1117-1122.

Kumar R, Binkley N, Vella A. Effect of phylloquinone supplementation on glucose homeostasis in humans. Am J Clin Nutr. 2010;92:1528-32.

Lamb JJ, Holick MF, Lerman RH, Konda VR, Minich DM, Desai A, Chen TC, Austin M, Kornberg J, Chang JL, Hsi A, Bland JS, Tripp ML. Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D₃, and vitamin K₁ produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome. Nutr Res. 2011;31:347-55.

Lerner RG, Aronow WS, Sekhri A, Palaniswamy C, Ahn C, Singh T, Sandhu R, McClung JA. Warfarin use and the risk of valvular calcification. J Thromb Haemost. 2009;7:2023-7.

Lurie Y, Loebstein R, Kurnik D, Almog S, Halkin H. Warfarin and vitamin K intake in the era of pharmacogenetics. Br J Clin Pharmacol. 2010;70:164-70.

Maree AO, Jneid H, Palacios IF, Rosenfield K, MacRae CA, Fitzgerald DJ. Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target. Curr Pharm Des 2007;13:2656-2661.

Martini LA, Catania AS, Ferreira SR. Role of vitamins and minerals in prevention and management of type 2 diabetes mellitus. Nutr Rev. 2010;68:341-54.

Matsumoto Y, Mikuni-Takagaki Y, Kozai Y, Miyagawa K, Naruse K, Wakao H, Kawamata R, Kashima I, Sakurai T. Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate. Osteoporos Int. 2009;20:1863-72.

Mazzini MJ, Schulze PC. Proatherogenic pathways leading to vascular calcification. Eur J Radiol. 2006;57:384-9.

McLean RR, Booth SL, Kiel DP, et al. Association of dietary and biochemical measures of vitamin K with quantitative ultrasound of the heel in men and women. Osteoporos Int. 2006;17:600-607.

Morgan SL. Nutrition and bone: it is more than calcium and vitamin D. Womens Health (Lond Engl). 2009;5:727-37.

Napolitano M, Mariani G, Lapecorella M. Hereditary combined deficiency of the vitamin K-dependent clotting factors. Orphanet J Rare Dis 2010; 14;5:21.

O’Connor E, Mølgaard C, Michaelsen KF, Jakobsen J, Cashman KD. Vitamin D-vitamin K interaction: effect of vitamin D supplementation on serum percentage undercarboxylated osteocalcin, a sensitive measure of vitamin K status, in Danish girls. Br J Nutr. 2010;104:1091-5.

Rees K, Guraewal S, Wong YL, Majanbu DL, Mavrodaris A, Stranges S, Kandala NB, Clarke A, Franco OH. Is vitamin K consumption associated with cardio-metabolic disorders? A systematic review. Maturitas. 2010;67:121-8.

Rejnmark L, Vestergaard P, Charles P, et al. No effect of vitamin K1 intake on bone mineral density and fracture risk in perimenopausal women. Osteoporos Int. 2006;17:1122-1132.

Roman E, Fear NT, Ansell P, et al. Vitamin K and childhood cancer: analysis of individual patient data from six case-control studies. Br J Cancer. 2002;86:63-69.

Schlieper G, Westenfeld R, Krüger T, Cranenburg EC, Magdeleyns EJ, Brandenburg VM, Djuric Z, Damjanovic T, Ketteler M, Vermeer C, Dimkovic N, Floege J, Schurgers LJ. Circulating nonphosphorylated carboxylated matrix gla protein predicts survival in ESRD. J Am Soc Nephrol. 2011 Feb;22:387-95.

Schurgers LJ, Dissel PE, Spronk HM, et al. Role of vitamin K and vitamin K-dependent proteins in vascular calcification. Z Kardiol. 2001;90 Suppl 3:57-63.

Shea MK, Gundberg CM, Meigs JB, Dallal GE, Saltzman E, Yoshida M, Jacques PF, Booth SL. Gamma-carboxylation of osteocalcin and insulin resistance in older men and women. Am J Clin Nutr. 2009;90:1230-5.

Shea MK, O’Donnell CJ, Hoffmann U, Dallal GE, Dawson-Hughes B, Ordovas JM, Price PA, Williamson MK, Booth SL. Vitamin K supplementation and progression of coronary artery calcium in older men and women. Am J Clin Nutr. 2009;89:1799-807.

Sogabe N, Maruyama R, Baba O, Hosoi T, Goseki-Sone M. Effects of long-term vitamin K(1) (phylloquinone) or vitamin K(2) (menaquinone-4) supplementation on body composition and serum parameters in rats. Bone. 2011;48:1036-42.

Strople J, Lovell G, Heubi J. Prevalence of subclinical vitamin K deficiency in cholestatic liver disease. J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):78-84. Iwamoto J, Sato Y, Takeda T, Matsumoto H. High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature. Nutr Res. 2009;29:221-8.

Tamura T, Morgan SL, Takimoto H. Vitamin K and the prevention of fractures. Arch Intern Med. 2007;167:94

Tucker KL. Osteoporosis prevention and nutrition. Curr Osteoporos Rep 2009;7:111-7.

van Hasselt PM, de Vries W, de Vries E, Kok K, Cranenburg EC, de Koning TJ, Schurgers LJ, Verkade HJ, Houwen RH. Hydrolysed formula is a risk factor for vitamin K deficiency in infants with unrecognised cholestasis. J Pediatr Gastroenterol Nutr. 2010;51:773-6.

Villines TC, Hatzigeorgiou C, Feuerstein IM, O’Malley PG, Taylor AJ. Vitamin K1 intake and coronary calcification. Coron Artery Dis. 2005;16:199-203.

Villines TC, O’Malley PG, Feuerstein IM, Thomas S, Taylor AJ. Does prolonged warfarin exposure potentiate coronary calcification in humans? Results of the warfarin and coronary calcification study. Calcif Tissue Int. 2009;85:494-500.

Vokó Z, de Brouwer S, Lubsen J, Danchin N, Otterstad JE, Dunselman PH, Kirwan BA. Long-term impact of secondary preventive treatments in patients with stable angina. Eur J Epidemiol. 2011;26:375-83.

Yoshida M, Jacques PF, Meigs JB, Saltzman E, Shea MK, Gundberg C, Dawson Hughes B, Dallal G, Booth SL. Effect of vitamin K supplementation on insulin resistance in older men and women. Diabetes Care 2008;31:2092-6.

Zwart SR, Booth SL, Peterson JW, Wang Z, Smith SM. Vitamin K status in spaceflight and ground-based models of spaceflight. J Bone Miner Res. 2011;26:948-54.


Kursübergreifende Literaturangaben zu Vitaminen und Spurenelementen

Biesalski HK, Biscoff SC, Puchstein C. Ernährungsmedizin. Nach dem neuen Curriculum Ernährungsmedizin der Bundesärztekammer. 4. Auflage. Georg Thieme Verlag, Stuttgart 2010

Bundesinstitut für gesundheitllichen Verbraucherschutz und Veterinärmedizin. Toxikologische und ernährungsphysiologische Aspekte der Verwendung von Mineralstoffen und Vitaminen in Lebensmitteln. Teil I: Mineralstoffe (einschließlich Spurenelemente). Vorschläge für Regelungen und Höchstmengen zum Schutz des Verbrauchers vor Überdosierung beim Verzehr von Nahrungsergänzungsmitteln (NEM) und angereicherten Lebensmitteln. Januar 2002

Cliniguía. Actualización de diagnóstico y terapéutica. EviScience Publicaciones 2011

Colastra J: Lamberts. Manual de Nutrición Ortomolecular. El manual de consulta imprescindible. SIE Consultantts sl 2010

D-A-CH (2000) Deutsche Gesellschaft für Ernährung (DGE), Österreichische Gesellschaft für Ernährung (ÖGE), Schweizerische Gesellschaft für Ernährungsforschung (SGE), Schweizerische Vereinigung für Ernährung (SVE): Referenzwerte für die Nährstoffzufuhr. 1. Auflage, Umschau/Braus Verlag, Frankfurt am Main

Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung: Referenzwerte für die Nährstoffzufuhr. 1. Auflage, 5., korrigierter Nachdruck, Neuer Umschau Buchverlag, Neustadt an der Weinstraße, 2013

Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung: Referenzwerte für die Nährstoffzufuhr. Verfügbar unter: https://www.dge.de/wissenschaft/referenzwerte/ (eingesehen am 07.09.2023)

Dietl H., Ohlenschläger G. (2003) Handbuch der Orthomolekularen Medizin. Karl F. Haug Verlag, Stuttgart

Domke A, Großklaus R, Niemann B, Przyrembel H, Richter K, Schmidt E, Weißenborn A, Wörner B, Ziegenhagen R: Verwendung von Mineralstoffen in Lebensmitteln. Toxikologische und ernährungsphysiologische Aspekte Teil II Bundesinstitut für Risikobewertung. Verfügbar unter: http://www.bfr.bund.de/cm/350/verwendung_von_mineralstoffen_in_lebensmitteln_bfr_wissenschaft_4_2004.pdf (eingesehen am 07.09.2023)

Einkaufs-und Ernährungsverhalten in Deutschland TNS-Emnid-Umfrage des Bundesministerium für Ernährung und Landwirtschaft, BMEL, (2014).

Europäische Richtlinie (2008/100/EG) vom 28. Oktober 2008 über die Nährwertkennzeichnung von Lebensmitteln hinsichtlich der empfohlenen Tagesdosen, der Umrechnungsfaktoren für den Energiewert und der Definitionen online verfügbar unter: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:32008L0100:DE:HTML (eingesehen am 07.09.2023)

Europäische Empfehlungen: European Micronutrient Recommendations Aligned (EURRECA). Verfügbar unter: http://www.eufic.org/en/collaboration/article/european-micronutrient-recommendations-aligned (eingesehen am 07.09.2023)

Food and Nutrtition Information Center der US Regierung (DRI-Empfehlungen) verfügbar unter: https://www.nal.usda.gov/fnic/dri-nutrient-reports (eingesehen am 07.09.2023)

Food Standards Agency (2002) Expert Group on Vitamins and Minerals. Review of Molybdenum

Food Standards Agency (2003) Safe Upper Levels for Vitamins and Minerals. Expert Group on Vitamins and Minerals, May 2003

Gröber U: Orthomolekulare Medizin. Ein Leitfaden für Apotheker und Ärzte. 3. Auflage. Wissenschaftliche Verlagsgesellschaft mbH Stuttgart 2008

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Hernandez Ramos F: Antienvejecimiento con nutrición ortomolecular. Integral 2007

Institute of Medicine: Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. National Academy Press, Washington, 2001

Koula-Jenik H, Kraft M, Miko M, Schulz RJ: Leitfaden Ernährungsmedizin. Urban & Fischer 2006

Otten JJ, Pitzi-Hellwig J, Meyers L (Eds): Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. The National Academies Press, Washington DC 2006

Richtlinie der European Food Safety Authority, EFSA, mit dem Titel „Scientific Committee on Food, Scientific Panel on Dietetic Products, Nutrition and Allergies: tolerable Upper Intake Levels for Vitamins and minerals. February 2006“.

Subcommittee on the Tenth Edition of the RDAs, Food and Nutrition Board, Commission on Life Sciences, National Research Council: Recommended Dietary Allowances: 10th Edition. National Academy Press, Washington DC, 1989

Vollwertig essen und trinken nach den 10 Regeln der DGE verfügbar unter: http://www.dge.de/modules.php?name=Content&pa=showpage&pid=15 (eingesehen am 07.09.2023)

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